Local church going the distance for tornado victims

JAMES ISLAND, SC (WCSC) -?Members of Harbor Light Baptist Church are collecting?supplies to drive more than 600 miles north and hand-deliver to people in what's left of Henryville, Indiana.

"Many of them lost everything," said Harbor Light pastor Keith Burgess.?"Literally everything they have."

Burgess believes in giving but his ties to the town of less than 2,000 people go much deeper. For three years he was a minister in Henryville. His daughter Marie Perry graduated from Henryville high school in 2003. And many of the families friends are still back in Indiana.

Burgess says watching the tornado level homes, take away cars and destroy the town's only school took a toll on him.

"It just hits you in the stomach," said Burgess. "You just wonder what kind of damage is going on and?who might be hurt. I just began to pray and as a Christian I knew I had to do something even at that moment."

With the help of Marie, who originally brought the idea to him, the congregation and the church's?mascot Harby, Harbor Light started taking donations.

The church is looking for everything from bottled water to toilet paper, laundry detergent?to towels.

"It's more of your everyday items that you need that you use on an everyday basis," said Perry,?who says even small items are bound to make big differences.

"People have been absolutely amazing from day one I was getting donations."

Perry, her father and other church volunteers will leave before the sun rises Friday morning to bring the donations to the people who need them most in Henryville and try to pick up their faith in any way they can.

"I'm really nervous but I know we're going up there for a good cause and I'm ready to take it head on," said Perry.?"I'm going to do what I can do for all the victims."

To donate, just stop by?Harbor Light Church at 1300 Fort Johnson Road on James Island. Time to donate will run out at sundown Thursday so a truck can be packed and gassed up for the trip to the Hoosier State.

Copyright WCSC 2012.? All rights reserved.

Source: http://jamesisland.live5news.com/news/news/66626-local-church-going-distance-tornado-victims

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Futurity.org ? Cancer drug may stymie lung disease

"Pulmonary fibrosis is the most common of the interstitial lung diseases, with a fatality rate in line with cancer,? says study author Zea Borok. ?These findings have the potential to provide an alternative treatment for patients afflicted by this debilitating disease." (Credit: Pan Xunbin / Shutterstock)

USC (US) ? Researchers have identified a target in lung cells that may lead to new treatments for a progressive disease that ultimately robs a patient of the ability to breathe.

Characterized by scarring of the lung, idiopathic pulmonary fibrosis affects about 128,000 people in the United States, with about 48,000 new cases diagnosed annually, according to the Coalition for Pulmonary Fibrosis. Lung damage caused by the disease can?t be repaired, and treatment has focused on improving quality of life.

As reported in the Journal of Biological Chemistry, the researchers discovered that inhibiting certain proteins blocks the interaction between two cellular pathways thought to contribute to the disease.

?There is very little research available about the mechanisms that underlie direct interactions between these cell signaling pathways, although previous studies have suggested that there is crosstalk between the two,? says Zea Borok, professor of medicine and biochemistry and molecular biology at University of Southern California and senior author of the study.

?Anti-inflammatory treatments that traditionally have been used for pulmonary fibrosis are uniformly ineffective. Our research suggests a new approach to treat a disease that is currently incurable.?

A cell signaling pathway consists of a series of signals that regulate cell behavior; studying these pathways and how information is transmitted along them may help shed light on disease origins and therapies.

Using rat lung cells, Borok and colleagues showed that the Wnt/?-catenin and transforming growth factor-? signaling pathways directly interact with one another. The interaction appears to increase expression of the ?-smooth muscle actin protein, a hallmark of a biological process associated with fibrosis formation. The researchers confirmed that the interaction also occurs in human lung cells, and found that the interactions are dependent on the CREB-binding protein (CBP).

The researchers suggest using ICG-001, an experimental CBP inhibitor developed by co-author Michael Kahn, a USC provost professor in medicine and pharmacy, to stymie the pathway interaction.

They posit that ICG-001, which has been shown to be safe for clinical use in colorectal cancer patients, could be used as treatment for pulmonary fibrosis. The next step is to study its efficacy in fibrosis patients.

?Pulmonary fibrosis is the most common of the interstitial lung diseases, with a fatality rate in line with cancer,? Borok says. ?These findings have the potential to provide an alternative treatment for patients afflicted by this debilitating disease.?

Researchers from the City of Hope Beckman Research Institute collaborated on the project. Beiyun Zhou, assistant professor of medicine at the Keck School, who performed most of the work during her post-doctoral training in Borok?s laboratory is first author of the study that was supported by the Hastings Foundation, Whittier Foundation, and National Institutes of Health.

More news from USC: http://uscnews.usc.edu/

Source: http://www.futurity.org/health-medicine/cancer-drug-may-stymie-lung-disease/

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Hearst Hits 100k Comso App Subscribers En Route To 1 Million Paying Digital Readers

Another milestone for old-school print magazines moving into a digital future: Cosmopolitan says that it now has 100,000 people paying to read the digital edition of its monthly fashion/beauty/lifestyle magazine. That puts publisher, Hearst, one step closer to a target set by president David Carey last November to rack up one million paying subscribers across all of its non-print editions this year. The 100,000 readers, Hearst says, come from its presence on a number of newsstands, including Apple, Zinio, Barnes & Noble and Amazon Kindle, where prices go from $1.99 for a one-month subscription to $19.99 for a full year of the magazine. It's not clear which of these newsstands is selling the most at the moment (we've asked). Zinio was the first of these launched by Hearst back in 2005, but the boom in digital reading, and specifically paying for the privilege, has really only taken off in the last couple of years with the rise of e-reading devices and tablets like the iPad and Kindle, and so these may be the storefronts doing the most business for Hearst at the moment.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Rbj4KgEWF0c/

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Mitt Romney Wins: Ohio Primary Results 2012

By Reuters

WUKAN, China -- Residents of a southern Chinese fishing village gathered on Saturday to elect a new administrative authority that many hail as a model for greater grassroots democracy in China following an uncompromising standoff over land grabs and abuse of power.

Wukan, nestled on the Guangdong coast with a picturesque harbor flanked by hills, has emerged from nowhere as a symbol of rural activism and electoral reforms nationwide, embracing rare freedoms granted by provincial authorities in December to defuse a major flashpoint.

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Anger at corrupt local officials turned to fury last September when villagers ransacked the Wukan government offices. Things boiled over again in December, when villagers drove out authorities and barricaded themselves in for 10 days before provincial officials stepped in to resolve the dispute, offering new elections.

Villagers defiant as government creates new narrative

Unlike the many flareups over land grabs and corruption across China every year, Wukan residents have now moved beyond organized protest to organized politics in a gritty bid to win back illegally sold farmland and safeguard future rights.

Some of the 12,000 residents gathered outside a school on an overcast morning, eager to cast ballots for candidates vying for seats on a seven-person village committee. Many are backing former protest leaders, including those jailed in December.

While village elections have been permitted for decades, Wukan has pushed the boundaries, led by a visionary rebel village leader turned party secretary and a vanguard of young activists able to unify the village against higher authorities.

PhotoBlog: Chinese villagers defy government in standoff over land rights

"For the first time in decades, this is an opportunity for democracy. Both myself and the villagers like this," said Lin Zuluan, Wukan's respected 67-year-old party secretary, a candidate to lead the village committee.

Anger over land grabs has captured the attention of China's leadership. Premier Wen Jiabao recently vowed to make village committee elections an authentic channel for public opinion, acknowledging China has failed to give adequate protection against rural land seizures.

Rebellious Chinese village takes baby steps toward democracy

"The root of the problem is that the land is the property of the farmers, but this right has not been protected in the way it should be," said Wen during a trip to Guangdong in February.

The Wukan experience has proved a beacon for civil rights activists, academics and journalists, who have flocked to the village to observe the polls.

"Wukan is an example for us," said Hua Youjuan, a village chief from Huangshan in eastern China, where villagers have also rallied against corruption.

"What Wukan has achieved through its solidarity is something we can learn from."

Behind-the-scenes influence
In a sign of growing international interest, the U.S. government sent an observer to the poll. "We continue to monitor developments in Wukan closely," a U.S. diplomat who asked not to be identified said.

The polls follow a months-long struggle that saw villagers clash with riot police, ransack government offices, expel a corrupt old guard and form a self-administrative authority. It all came to a head in December, when villagers barricaded themselves in against riot police.

Peter Parks / AFP - Getty Images

Residents of Wukan fill in forms during voting in village elections on Saturday.

Guangdong provincial authorities, led by ambitious Communist Party leader Wang Yang, intervened, naming the rebel leader Lin as party secretary in a surprising concession.

Behind the scenes, authorities at the city and county level have been exerting a high degree of control. Some fear clans and allies of former village chief Xue Chang, whom many accuse of pocketing millions from selling off collective farmland, are vying to maintain influence.

Journalist beatings erase Wukan optimism

Xue Jianwan, the daughter of Xue Jinbo, a protest leader who was abducted and died in police detention in December, said senior local officials recently urged her to drop from running as a candidate for the village committee.

She said taking part in the election might mean she could no longer continue in her job as a teacher given electoral rules.

"The more they don't want me to take part, the more I want to," said Xue in an interview before election day.

Other young leaders, who played a key role in publicising corruption that saw hundreds of hectares of Wukan farmland sold off in illegal deals, have spoken of extensive surveillance, police pressure and fears of reprisals.

In February, Wukan elected an election committee to oversee Saturday's proceedings. Now the stakes are higher.

The seven-member village committee, including a village chief and two deputies, will have power over local finances and the sale and apportioning of collectively owned village land.

Residents hope the frequent practice of higher officials controlling lucrative land deals will become a thing of the past.

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Copyright 2011 Thomson Reuters. Click for restrictions.

Source: http://worldnews.msnbc.msn.com/_news/2012/03/03/10567378-opportunity-for-democracy-rebel-chinese-village-votes

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Online Marketing and Business Consulting ? Mobile websites vs ...

Adobe just published an article that I wrote a few months ago, which talks about the decision to create an app or a website / web app. As part of the article, I interviewed one of my clients, Rage Digital. They specialize in building iPhone / iPad applications and I was interested to learn from their experiences in building applications for some of the biggest companies around, including HTC, which is a featured company in the article. Their ?you? marketing campaign was a very interesting mix of online and offline efforts that were nicely tied together and required the user to engage with their advertisement through the Google Goggles app.

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Source: http://www.kleinnewmedia.com/mobile-websites-vs-mobile-apps/

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